Mast Cells, tissue-specialized cell of our body's immune system, which respond to antigen with immunosuppressive or anti-inflammatory properties. Mast cells also mediate many non-inflammatory responses such as immunosuppressive and anti-allergic reactions.
Mast Cells are divided into two types: T-cells and B-cells. T-cells, as their name suggests, are responsible for the production of antibodies against specific allergens. T-cells can be found in all body fluids such as sweat and saliva. However, they are most commonly found in lymphatic fluids (in spleen, lymph nodes and bone marrow) and they are primarily responsible for the production of antibodies that neutralize invading substances.
The other type of Mast Cells is known as B-cells. B-cells are also responsible for producing antibodies that may kill pathogens or foreign entities. B-cells are also present in blood and lymph fluids. In rare cases, B-cells may produce antibodies that are produced to fight tumors.
Mast cells are activated when an allergen or certain substance is present. When the immune system reacts with an attack on a substance or object, mast cells produce antibodies that bind to the substance or object. These antibodies trigger an inflammatory response within the body. In some cases, these inflammatory reactions can lead to swelling of the capillaries and eyes, the eyes can darken, and inflammation can occur between the cornea and the lens.
Mast cells can also produce cytokines and chemokines, chemicals that signal the activation of cells in the body. Mast cells can also stimulate the body's natural defenses by producing antibodies and interferons that help the body fight or prevent infections.
Some drugs, such as beta blockers, can suppress mast cells
Other drugs, such as corticosteroids, can suppress the release of thymic stem cells by the bone marrow. Certain types of chemotherapy drugs can suppress B cell production by suppressing T cell production.
Since mast cells are found in many parts of the body and can play a role in many diseases, it is important that we know how to protect them. They are important for fighting infections, immunity, and cell function. Some drugs that affect mast cell activity include beta-blockers, antibiotics, anti-interferons, cyclophosphamide, photodynamic therapy, thyroiditis drugs, immunosuppressants chemotherapy drugs, immunodeficiency drugs, and immunocatabolic drugs such as prednisone and azathioprine. However, mast cells are also susceptible to radiation, environmental toxins, toxic chemicals, or infection.
The ability of mast cells to fight disease and infection is essential to the existence of healthy cells and tissues. They also have important roles in metabolizing and synthesizing vital hormones. When mast cells become dysfunctional, they become the main causes of damage in various parts of our body.
In order to stop the disease process, the mast cell stimulant that is most useful is a compound called EGCG, or Epigallocatechin Gallate. This compound is an antioxidant and has been shown to slow down the aging process and in turn improve our health. When using EGCG to treat cancer, it helps to block the activity of the carcinogens and their oxygenated derivatives. which is known as reactive oxygen species. ROSs). It can also prevent damage to normal tissue and DNA by oxidation by the carcinogens.
Other antioxidants that can be used in the treatment of cancer include EGCG, Coenzyme Q10, vitamin E, glutathione, selenium, quercetin, and flavonoids.
